Predicting the evolution of genetic mutations

Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see how specific genetic mutations can combine ...

Mutation reduces energy waste in plants

To this end, the team identified several thousand proteins, determined their respective amounts in mutant and reference lines and combined the findings with measurements of photosynthetic performance. Their findings were ...

Engineers model mutations causing drug resistance

Whether it is a drug-resistant strain of bacteria, or cancer cells that no longer react to the drugs intended to kill them, diverse mutations make cells resistant to chemicals, and "second generation" approaches are needed. ...

Gene switch ENO identified as a tomato fruit regulator

A team of researchers from Spain, Germany and France has identified the gene switch ENO (excessive number of floral organs) as a tomato fruit regulator. In their paper published in Proceedings of the National Academy of Sciences, ...

Scientists optimize prime editing for rice and wheat

Many genetic and breeding studies have shown that point mutations and indels (insertions and deletions) can alter elite traits in crop plants. Although nuclease-initiated homology-directed repair (HDR) can generate such changes, ...

Study connects specific genes with defective social behavior

Animals rely on group behavior to survive, whether it's fish swimming together to avoid predators or humans sharing knowledge with each other. But despite the importance of such social interactions, scientists do not have ...

New insights into evolution: Why genes appear to move around

Scientists at Uppsala University have proposed an addition to the theory of evolution that can explain how and why genes move on chromosomes. The hypothesis, called the SNAP Hypothesis, is presented in the scientific journal ...

Study finds 'silent' genetic variations can alter protein folding

Proteins, the workhorse of the human cell, help digest our food, carry oxygen through the body, fight off invading microbes, and so much moreā€”but they only function when folded properly into specific, three dimensional ...

SNIPRs take aim at disease-related mutations

A typo appearing in the draft of a novel is no great calamity. Nature, however, is often less forgiving of errors. A change in just one letter of the genetic code can have catastrophic consequences for human health.

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