How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details of mutation-induced subtle ...
Biochemistry
Apr 16, 2024
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Flowers may look delicate—but flowering plants, what scientists call angiosperms, are one of the most successful evolutionary organisms on the planet. Including more than 350,000 known species, they dominate the ecological ...
Evolution
Apr 10, 2024
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The Janus kinase 2 (JAK2) protein mediates signaling from several cytokine receptors in the regulation of hematopoiesis and immune responses. Somatic mutations in human JAK2 lead to constitutive activation and cytokine-independent ...
Molecular & Computational biology
Apr 4, 2024
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16
New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.
Evolution
Mar 29, 2024
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162
More than half a million cats in the United States could be at risk of a severe or even fatal neurological reaction to the active ingredient in some top-selling parasite preventatives for felines.
Plants & Animals
Mar 28, 2024
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39
Enzymes, nature's remarkable biocatalysts, play an integral role in various aspects of daily life. Consider the awe-inspiring sight of fireflies lighting up a summer night. Their captivating glow serves not just to enchant ...
Biotechnology
Mar 20, 2024
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1
After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo. This is according to a new study led by researchers ...
Cell & Microbiology
Mar 14, 2024
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5
A high-throughput genetic screening of meiotic crossover rate mutants in Arabidopsis thaliana has unraveled a century-old mystery in the life sciences.
Cell & Microbiology
Mar 8, 2024
5
97
New research finds around a quarter of Labrador retriever dogs face a double-whammy of feeling hungry all the time and burning fewer calories due to a genetic mutation. The results are published in the journal Science Advances.
Molecular & Computational biology
Mar 6, 2024
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139
A multi-institutional team of geneticists in China has discovered the gene mutation responsible for a brown coat in giant pandas. In their study, published in the journal Proceedings of the National Academy of Sciences, the ...
