UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes—organelles that serve as protein factories for cells—as well as a surprising part in neurodevelopmental ...
Cell & Microbiology
Mar 29, 2022
0
99
The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now ...
Biochemistry
Mar 14, 2022
0
348
Scientists have obtained the first high-resolution 3D image of nebulin, a giant actin-binding protein that is an essential component of skeletal muscle. This discovery has brought to light the chance to better understand ...
Biotechnology
Feb 18, 2022
1
125
A mutated protein causes the genetic disease cystic fibrosis. Now, researchers have solved the structure of the protein and how certain drugs bind to it, unveiling their mode of action.
Cell & Microbiology
Jan 7, 2022
0
590
Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...
Cell & Microbiology
Dec 28, 2021
0
254
For the first time, researchers have constructed a detailed 3D structure of human SAGA, a 20-piece molecular machine crucial to human life.
Molecular & Computational biology
Nov 23, 2021
0
50
A recent statistical study has revealed some of the constraints and directions in the evolution of the structure and function of proteins. Better models of protein structural dynamics may allow researchers to understand more ...
General Physics
Oct 14, 2021
0
93
Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems. Originally created ...
Molecular & Computational biology
Oct 4, 2021
0
83
Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome ...
Cell & Microbiology
Sep 23, 2021
0
13
Reducing naturally occurring errors in protein synthesis (production) improves both health and lifespan, finds a new study in simple model organisms led by researchers at UCL and MRC London Institute of Medical Sciences.
Cell & Microbiology
Sep 14, 2021
0
262
