A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research—live, human muscle cells grown on scaffolds fixed on tiny chips—lifted off, climbed, and disappeared into the sky to the International Space ...
Space Exploration
Jul 25, 2024
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33
Future missions to the moon and Mars must address many challenges, including preventing loss of bone and muscle tissue in astronauts. Research on the International Space Station is helping to address this challenge.
Space Exploration
May 20, 2024
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18
Even intense exercise by astronauts cannot compensate for muscle atrophy caused by microgravity. Atrophy occurs, in part, by way of an underlying mechanism that regulates calcium uptake. Recent research has shown exposure ...
Space Exploration
Apr 17, 2024
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8
Researchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle. They studied mice with the Msi2 gene knocked ...
Cell & Microbiology
Sep 11, 2023
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8
Scientists from Tokyo Metropolitan University have discovered that a protein called platelet-derived growth factor subunit B (PDGF-B) is continuously secreted from skeletal muscle cells and helps to repair muscles by encouraging ...
Cell & Microbiology
Jan 16, 2023
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8
WNT signaling is crucial for the development of organisms and the maintenance of tissue homeostasis, since the WNT messengers are involved in a variety of cellular functions. In skeletal muscle, for example, they can increase ...
Cell & Microbiology
Dec 13, 2022
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10
Researchers from Tokyo Metropolitan University have developed a way to characterize the force generated by contracting myotubes, precursors to skeletal muscle fiber, combining electrostimulation and analysis of wrinkles in ...
Biochemistry
Sep 5, 2022
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95
Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, ...
Molecular & Computational biology
Mar 14, 2022
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288
Many kids dream of growing up to be astronauts; but the downside of spending extended amounts of time in low gravity is that astronauts' muscles tend to shrink and weaken through disuse. Now, researchers from Japan have identified ...
Molecular & Computational biology
Jul 8, 2021
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17
Researchers from the University of Tsukuba have sent mice into space to explore effects of spaceflight and reduced gravity on muscle atrophy, or wasting, at the molecular level.
Space Exploration
May 11, 2021
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