Genome editing: Efficient CRISPR experiments in mouse cells

In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the ...

First mouse, now human, lab-grown eye tissue

Producing retinal tissue from human embryonic stem cells is now possible thanks to a team of researchers led by Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan.

Finding a lethal parasite's vulnerabilities

An estimated 100 million people around the world are infected with Strongyloides stercoralis, a parasitic nematode, yet it's likely that many don't know it. The infection can persist for years, usually only causing mild symptoms. ...

Fast track to mouse modeling

What genes are responsible for the development of breast cancer? What are the brain cell mutations that lead to the onset of Alzheimer's? To find new therapies, scientists have to understand how diseases are triggered at ...

Mobile devices serve as own mice with optical sensing (w/ Video)

(PhysOrg.com) -- The same inexpensive, but high-quality optical sensors employed in the common computer mouse can enable small mobile phones and digital music players to be used as their own pointing and gestural input devices, ...

The living fossils of brain evolution

(Phys.org) -- In the course of its evolution, the architecture of the mouse brain may have barely changed. Similar to the tiny ancestors of modern mammals that lived about 80 million years ago, nerve cells in the mouse visual ...

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