Sweet! How C. difficile toxin A enters intestinal cells

Clostridiodes difficile infection has become a leading cause of severe, sometimes fatal diarrheal illness. It flourishes best in hospitals and long-term care facilities where people are on long-term antibiotic treatment, ...

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led by ...

Mammoth moves: frozen cells come to life, but only just

A team of scientists in Japan has successfully coaxed activity from 28,000-year-old cells from a frozen mammoth implanted into mouse cells, but the woolly mammal is unlikely to be walking among us soon.

Molecular puzzle reveals unknown stages of fetal development

By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilised egg to living ...

Activating tooth regeneration in mice

Most reptiles and fish have multiple sets of teeth during their lifetime. However, most mammals, such as humans, have only one set of replacement teeth and some mammals, like mice, have only a single set with no replacement. ...

Lipoproteins behave 'almost like a tiny Velcro ball'

Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first ...

Mechanism for turning skin cells into blood stem cells uncovered

Researchers have succeeded in converting human skin cells into blood stem cells in an international collaboration project. "This is a first step on the way to generating fully functional blood stem cells in a petri dish which, ...

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