A method to activate targeted drugs, or smart drugs, only at the selected site of action, an approach that improves the drug's therapeutic effect and minimizes side effects, has been developed in a study led by Georgia State ...
Materials Science
May 17, 2018
0
154
Ferrocene is an emergent organic-metal hybrid compound, and its accidental discovery has led to the rapid development of organometallic chemistry. Aside from its interesting structure, which consists of an iron atom sandwiched ...
Analytical Chemistry
Aug 29, 2023
0
343
Most drugs are small molecules that bind firmly to a specific target—some molecule in human cells that is involved in a disease—in order to work. For example, a cancer drug's target might be a molecule that is abundant ...
Biochemistry
Sep 29, 2023
0
59
Researchers from the Max Planck Institute of Biophysics in Frankfurt, and Mount Sinai School of Medicine in New York have provided the first atomic-level glimpse of the proton-driven motor from a major group of ATP synthases, ...
Biochemistry
Aug 3, 2010
2
1
Deep learning has radically changed the field of artificial intelligence. Now neural networks are revolutionizing the way that we discover new drugs. We talk to Francesca Grisoni, assistant professor at the department of ...
Biotechnology
Sep 16, 2021
0
240
(Phys.org)—A University of Michigan biophysical chemist and his colleagues have discovered the smallest and fastest-known molecular switches made of RNA, the chemical cousin of DNA. The researchers say these rare, fleeting ...
Cell & Microbiology
Oct 7, 2012
0
0
(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...
Biotechnology
Feb 20, 2012
0
0
(Phys.org)—A review paper by UCD researchers describing how nanoparticles can gather a cloak of molecules onto themselves in the human body is featured on the front cover of Nature Nanotechnology.
Bio & Medicine
Dec 18, 2012
0
0
(Phys.org) —Researchers hope to hijack a natural process called RNA interference to block the production of proteins linked to disease and treat medical conditions for which conventional drugs do not work, including cancer, ...
Biochemistry
Sep 27, 2013
0
0
(PhysOrg.com) -- Building on a technique they used to produce nanomovies of RNA molecules in motion, researchers have created "high definition" versions of the animations that reveal even more details about how RNA changes ...
Cell & Microbiology
Apr 20, 2009
1
0
