Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

Toxins force construction of 'roads to nowhere'

Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into "roads to nowhere," redirecting the proteins away from other jobs that are key to proper ...

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