CRISPR off-switches: A path towards safer genome engineering?

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells. In fact, the first CRISPR-based therapeutic was recently approved ...

Missing gene in mouse sperm could explain infertility

Mice lacking a certain gene are unable to produce offspring because their sperm lack the connection between the tail and the head. A new thesis from the University of Gothenburg indicates a probable cause of male infertility.

New human gene cluster sequence discovered

Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...

Pioneering automated proteoform imaging

Investigators led by Neil Kelleher, Ph.D., professor of Medicine in the Division of Hematology and Oncology and of Biochemistry and Molecular Genetics, have developed an automated technique for imaging and identifying proteoforms ...

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