Bacteria encode hidden genes outside their genome; do we?

Since the genetic code was first deciphered in the 1960s, our genes have seemed like an open book. By reading and decoding our chromosomes as linear strings of letters, like sentences in a novel, we can identify the genes ...

Capturing DNA origami folding with a new dynamic model

Most people are familiar with the DNA double-helix. Its twisted ladder shape forms because the long pieces of DNA that make up our genome are exactly complementary—every adenine paired to a thymine, and every cytosine paired ...

Developing a machine learning model to explore DNA methylation

A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.

Biologists reveal how gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body ...

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