Researchers discover that protein switches functions to regulate DNA replication
One protein. One mechanism of action. Two biologically opposite effects.
One protein. One mechanism of action. Two biologically opposite effects.
Biotechnology
Jul 23, 2021
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2249
It took 13 years and one billion dollars to sequence the human genome, an enormous scientific undertaking that launched a new era of medicine. With today's advances in sequencing technology, that same task would have only ...
Nanomaterials
Jun 25, 2021
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343
All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets ...
Biotechnology
Jun 2, 2021
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11
A bacterial protein helps to stop transcription—the process of making RNA copies of DNA to carry out the functions of the cell—by causing the cellular machinery that transcribes the DNA to pause at the appropriate spots ...
Biotechnology
May 7, 2021
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82
A group of researchers at the Hong Kong University of Science and Technology (HKUST) has uncovered the mechanism of how DNA is being melted to start bacterial gene transcription and how one class of antibiotics inhibits this ...
Cell & Microbiology
May 5, 2021
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22
A research group working at Uppsala University has succeeded in studying 'translation factors' – important components of a cell's protein synthesis machinery—that are several billion years old. By studying these ancient ...
Molecular & Computational biology
Apr 29, 2021
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42
Telomeres are large nucleoproteins structures that cap the ends of chromosomes in eukaryotic cells. When a cell divides, a small portion of the telomere is lost due to the inherently incomplete process of genome replication. ...
Biotechnology
Apr 22, 2021
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197
Molecular cages created by Imperial researchers could lead to more targeted cancer drug delivery, causing greater efficiency and fewer side effects.
Bio & Medicine
Apr 7, 2021
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162
Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre (CNIO) have discovered how certain proteins ensure the repair of errors introduced ...
Molecular & Computational biology
Apr 6, 2021
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261
Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the MRN complex—the cell's DNA scissors. Using purified yeast proteins, they demonstrated that phosphorylation ...
Biotechnology
Mar 10, 2021
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12