How E. coli defends itself against antibiotics

Imagine that you have a very sore throat. You're sick, your throat hurts, and a visit to the doctor confirms that the pain is due to a bacterial infection. You get a prescription for antibiotics, which quickly sorts out your ...

Capturing DNA origami folding with a new dynamic model

Most people are familiar with the DNA double-helix. Its twisted ladder shape forms because the long pieces of DNA that make up our genome are exactly complementary—every adenine paired to a thymine, and every cytosine paired ...

Developing a machine learning model to explore DNA methylation

A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.

Biologists reveal how gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in every cell in the body ...

Newly discovered protein prevents DNA triplication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent. This means that, millions of times a day, a biochemical wonder takes place in the body: the copying ...

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