Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

Directing evolutionary changes

Since 1859, when Darwin's classic work "On the Origin of Species" was published, we have known that populations change over the course of time. The ability to adapt to changing surroundings is the basis for evolution and ...

'Molecular beacons' light up stem cell transformation

(Phys.org)—A novel set of custom-designed "molecular beacons" allows scientists to monitor gene expression in living populations of stem cells as they turn into a specific tissue in real-time. The technology, which Brown ...

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