Feedback loop maintains basal cell population

Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...

Singapore scientists discover how to control fate of stem cells

Scientists from the Genome Institute of Singapore (GIS), an institute of the Agency for Science, Technology and Research (A*STAR), in collaboration with the Cancer Science Institute of Singapore (CSI), have discovered how ...

Nanoneedle is small in size, but huge in applications

(PhysOrg.com) -- Researchers at the University of Illinois have developed a membrane-penetrating nanoneedle for the targeted delivery of one or more molecules into the cytoplasm or the nucleus of living cells. In addition ...

Researchers ID molecular link key for cell growth

(PhysOrg.com) -- When a cell is preparing to grow or replicate, it starts the way a monarch planning to expand his territory might: by identifying and marshaling the necessary resources, loading them onto the appropriate ...

Fungal biology: Finding yeast's better half

Scientists long believed that the fungal pathogen Candida albicans was incapable of producing haploid cells—which contain only one copy of each chromosome, analagous to eggs and sperm—for mating. Mixing of genes in sexual ...

The ribosome: A new target for antiprion medicines

New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...

A microbe's fountain of youth

The yeast S.pombe is one of the best-studied microbes in the world. First isolated from East African millet beer over a century ago, it's been used as a model organism in molecular and cell biology for the past sixty years. ...

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