How heart failure disrupts the cell's mitochondria

Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising ...

Meet the first Neanderthal family

The first Neanderthal draft genome was published in 2010. Since then, researchers from the Max Planck Institute for Evolutionary Anthropology have sequenced a further 18 genomes from 14 different archaeological sites throughout ...

Two hits to the mitochondria can cause severe anemia

Mitochondria may seem like small cogs in the complex machinery of the cell, but even little gears can drive big changes. Now, researchers from Japan have found that impairing mitochondria in two different ways can have a ...

Immune function remodeled by mitochondrial shape

A new study focused on the immune system's Th17 cells suggests that the shape and function of their mitochondria is important in autoimmune and inflammatory disorders, such as multiple sclerosis. T helper 17 (Th17) cells ...

Small proteins play big role in cellular energy balance

Scientists at Duke-NUS Medical School have discovered new molecular details of how cells ensure that their energy supply is adjusted to meet energy demand. Their study, carried out in collaboration with researchers at the ...

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