(PhysOrg.com) -- All proteins self-assemble in a fraction of the blink of an eye, but it can take a long time to mimic the process. And there has been no guarantee of success, even with the most powerful computers - until ...
Biochemistry
Jul 6, 2010
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As life propagated across Earth in the form of the widest variety of single-celled organisms, sometime between 3.5 and 1 billion years ago one such organism managed an evolutionary coup: Instead of devouring and digesting ...
Cell & Microbiology
Jul 28, 2023
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When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope—a sort of cellular traffic camera—University of Illinois chemists now can watch the way ...
Cell & Microbiology
Dec 9, 2014
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Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed ...
Cell & Microbiology
Sep 11, 2014
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You are taking a class on origami and Mr. Otaki asks you to fold that little red piece of paper into a very elaborate design. You have to do it in a very short time. You try your best but you fail. Your origami sucks!
Biochemistry
May 11, 2015
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Researchers from the Verstreken lab (VIB-KU Leuven) have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body. In addition to its well-known role as a protein chaperone, ...
Cell & Microbiology
Sep 7, 2018
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Research by the University of Southampton has provided new insight into the consequence of accumulated 'misfolded proteins' in neurodegenerative disorders, such as Prion and Alzheimer's disease.
Biochemistry
Feb 14, 2014
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Protein aggregates have a bad reputation in conditions such as Alzheimer's disease and Parkinson's disease, but in bacteria, inheritance of aggregates by daughter cells may help protect against the same toxic stresses that ...
Cell & Microbiology
Aug 28, 2018
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Scientists from the Florida campus of The Scripps Research Institute have uncovered a potentially important new therapeutic target that could prevent stress-related cell death, a characteristic of neurodegenerative diseases ...
Biochemistry
Jun 2, 2011
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Researchers discovered a new protein involved in the process that determines the fate of cells under stress and whether they fight to survive or sacrifice themselves for the greater good.
Cell & Microbiology
Apr 2, 2015
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