Study describes mechanism that regulates activity of memory gene

The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer's disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. ...

Studying epigenetic regulation at the single-molecule level

If one imagines the genome as an instruction manual for the functioning of a cell, every page of this manual is covered with annotations, highlights, and bookmarks. The role of some of these marks remains mysterious—do ...

RNA's 'joints' play key role in our gene expression, scientists find

University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work. The team, led by Chuan He, the UChicago John T. Wilson Distinguished Service Professor of Chemistry, Biochemistry ...

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