Related topics: genes · gene expression

Study describes mechanism that regulates activity of memory gene

The protein PKMzeta is known to be associated with long-term memory formation. Neurological disorders such Alzheimer's disease, as well as depression and aging, correlate with reduced levels of this protein in the brain. ...

Studying epigenetic regulation at the single-molecule level

If one imagines the genome as an instruction manual for the functioning of a cell, every page of this manual is covered with annotations, highlights, and bookmarks. The role of some of these marks remains mysterious—do ...

RNA's 'joints' play key role in our gene expression, scientists find

University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work. The team, led by Chuan He, the UChicago John T. Wilson Distinguished Service Professor of Chemistry, Biochemistry ...

From octopus to elephant: A molecular zoo of epigenetics

Our genes are encoded in the DNA sequence of the genome, which is highly similar across the diverse cell types of our body. Yet, each cell can only access those genes that are in an epigenetically permissive state. The epigenome ...

Endogenous retroviruses: Link to programmed aging found

The co-option between viruses and humans plays important roles during human evolution. Endogenous retroviruses (ERVs), belonging to long terminal repeat retrotransposons, are a relic of ancient retroviral infection, fixed ...

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