Researchers identify key player in cellular response to stress

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests. The findings, published ...

AI is helping to quantify enzyme activity

Without enzymes, an organism would not be able to survive. It is these biocatalysts that facilitate a whole range of chemical reactions, producing the building blocks of the cells. Enzymes are also used widely in biotechnology ...

Researchers take a fresh look at the Michaelis-Menten equation

Researchers from Aarhus University challenge one of the cornerstones of biochemistry, the Michaelis-Menten equation. They show that many enzymes in signaling pathways are independent of substrate concentration, because the ...

Scientists discover ancient enzymes evolve new tricks

Plants, herbivores, and pathogens are locked in a war for survival that is hundreds of millions of years old. Rooted in place and with no way to run, plants evolved complex, chemical-producing machinery in their cells to ...

Study tracks evolutionary history of metabolic networks

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...

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