Researchers take a fresh look at the Michaelis-Menten equation

Researchers from Aarhus University challenge one of the cornerstones of biochemistry, the Michaelis-Menten equation. They show that many enzymes in signaling pathways are independent of substrate concentration, because the ...

Scientists discover ancient enzymes evolve new tricks

Plants, herbivores, and pathogens are locked in a war for survival that is hundreds of millions of years old. Rooted in place and with no way to run, plants evolved complex, chemical-producing machinery in their cells to ...

Study tracks evolutionary history of metabolic networks

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...

BridgIT, a new tool for orphan and novel enzyme reactions

Effective protein engineering can give us control over the generated products inside a cell. However, for many of the biochemical reactions responsible for these products, we don't we don't know the specific protein or enzyme-producing ...

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