Making single-cell RNA sequencing widely available

Sequencing messenger RNA molecules from individual cells offers a glimpse into the lives of those cells, revealing what they're doing at a particular time. However, the equipment required to do this kind of analysis is cumbersome ...

Ribosome recycling as a drug target

Ludwig Maximilian University of Munich researchers have elucidated a mechanism that recycles bacterial ribosomes stalled on messenger RNAs that lack termination codons. The protein involved provides a potential target for ...

Study identifies new mechanism of RNA degradation in plants

The totality of RNA molecules in an organism at any one time is the product of a delicate dance. Genes must be "turned on," or expressed, in order to turn DNA into RNA and then that RNA into proteins that accomplish an organism's ...

How fungi help trees tolerate drought

In the transcriptome—the set of its messenger RNA molecules that reflects actual biochemical activity by the organism—of the most common ectomycorrhizal fungus Cenococcum geophilum, a team including DOE JGI researchers ...

In scientific first, researchers visualize proteins being born

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial ...

Scientists publish the first RNA interactome of the human nucleus

Studying sequence and function of DNA has been in the focus of life sciences for decades, but now the interest of many researchers has turned to the RNA. Today, many scientists believe that RNA molecules, together with a ...

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