Scientists at Scripps Research have discovered that a mysterious family of cellular proteins called OSCAs and TMEM63s are a novel class of mechanosensitive ion channels.
Cell & Microbiology
Nov 15, 2018
0
17
Worldwide, resistance to antibiotics is on the rise. In order to understand why bacteria are becoming immune to previously well-functioning drugs, scientists are penetrating ever deeper into the molecular structure of cells. ...
Cell & Microbiology
Oct 26, 2018
0
34
Biochemists at the University of Illinois have isolated a protein supercomplex from a bacterial membrane that, like a battery, generates a voltage across the bacterial membrane. The voltage is used to make ATP, a key energy ...
Cell & Microbiology
May 14, 2018
0
33
Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechanism that puts the brakes on an important cell signaling ...
Cell & Microbiology
May 7, 2018
0
74
An international team of researchers has determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light. Optogenetics is a relatively new technique that ...
Biotechnology
Nov 28, 2017
0
2
Membrane proteins make up approximately a quarter of all gene products and are the targets of over 50 percent of all modern pharmaceutical drugs. The inner mitochondrial membrane (IMM) proteome plays a central role in maintaining ...
Biochemistry
Apr 26, 2017
0
4
Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin.
Cell & Microbiology
Jan 11, 2017
0
475
In a collaborative study, scientists from MIPT and JINR (Joint Institute for Nuclear Research) have increased the accuracy of detecting valuable protein crystals of just a few microns in size. These small crystals are now ...
Biochemistry
Oct 20, 2016
0
6
Cell division is a fundamental process of life, producing two cells from one single cell at each cell division. During animal development, a fertilized egg divides many times, increasing the number of cells, which are precisely ...
Cell & Microbiology
Aug 12, 2016
0
11
An artificial mimic of a key light-sensitive molecule has been made by scientists at the University of Bristol. The work, published in Science, could lead to new ways of building light-sensitive artificial cells.
Biochemistry
Apr 4, 2016
0
28
