A new control system for synthetic genes
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
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28
Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development. The once radical idea that such changes in gene expression can be ...
Cell & Microbiology
Sep 26, 2022
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374
In a study published in the journal Genome Research, investigators in UC San Diego's Department of Computer Science and Engineering and Johns Hopkins University have illuminated the immunoglobulin (antibody) genes in 20 mammalian ...
Molecular & Computational biology
Aug 1, 2022
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12
Researchers at New York University have created artificial Hox genes—which plan and direct where cells go to develop tissues or organs—using new synthetic DNA technology and genomic engineering in stem cells.
Biotechnology
Jun 30, 2022
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220
Natural selection has produced mammals that age at dramatically different rates. Take, for example, naked mole rats and mice; the former can live up to 41 years, nearly ten times as long as similar-size rodents such as mice.
Cell & Microbiology
May 31, 2022
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73
In most mammals, females have two X chromosomes and males have one X and one Y chromosome in each of their cells. To avoid a double dose of X-linked genes in females, one of the Xs is silenced early in the developmental process. ...
Biotechnology
May 20, 2022
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37
Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether. An enzyme called ...
Cell & Microbiology
Mar 17, 2022
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70
A retired microscope and samples from studies on colloids and cellular signaling are among the cargo returning from the International Space Stationaboard the 24th SpaceX commercial resupply services mission. The Dragon ...
Space Exploration
Jan 26, 2022
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15
High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...
Cell & Microbiology
Sep 7, 2021
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16
The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he ...
Biotechnology
Sep 3, 2021
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