A new control system for synthetic genes

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

New algorithm helps identify antibody genes

In a study published in the journal Genome Research, investigators in UC San Diego's Department of Computer Science and Engineering and Johns Hopkins University have illuminated the immunoglobulin (antibody) genes in 20 mammalian ...

Scientists engineer synthetic DNA to study 'architect' genes

Researchers at New York University have created artificial Hox genes—which plan and direct where cells go to develop tissues or organs—using new synthetic DNA technology and genomic engineering in stem cells.

The secret to a longer lifespan? Gene regulation holds a clue

Natural selection has produced mammals that age at dramatically different rates. Take, for example, naked mole rats and mice; the former can live up to 41 years, nearly ten times as long as similar-size rodents such as mice.

Stabilizing chromosomes to tackle tumors

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off altogether. An enzyme called ...

The Spatial Mouse Atlas: New insights into cell fate

High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...

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