Scientists develop high-throughput mitochondria transfer device

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach ...

A host protein phosphatase restricts innate immune signaling

The adaptor proteins STING and MAVS are components of critical pathogen-sensing pathways that induce innate immunity. Phosphorylation of either adaptor results in activation of the type I interferon pathway and excessive ...

Inside mitochondria and their fascinating genome

Mitochondria are present in all eukaryotic cells: in our cells, in mammalian cells, in the cells of plants and even of fungi. Mitochondria produce energy for cells to function as multicellular organisms, and are known as ...

The surprising organisation of avian brains

Birds and mammals have the largest brains in relation to their body. Apart from that, however, they have little in common, according to scientific opinion since the 19th century: mammalian brains have a neocortex, i.e. a ...

Histone degradation after DNA damage enhances repair

DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...

New insight into mammalian stem cell evolution

The genes regulating pluripotent stem cells in mammals are surprisingly similar across 48 species, Kyoto University researchers report in the journal Genome Biology and Evolution. The study also shows that differences among ...

page 10 from 28