Interaction with lung cells transforms asbestos particles

A common building material, asbestos is the term used to describe a range of naturally growing minerals. Serious diseases, including mesothelioma and lung cancer, can arise decades after coming into contact with asbestos.

Directed protein evolution with CRISPR-Cas9

"Directed evolution" is the process by which scientists produce tailor-made proteins for cell biology, physiology and biomedicine in the laboratory. Based on this method, Max Planck researchers from Martinsried have now developed ...

Changes in cellular degradation hubs can lead to cancer

Cancer cells grow and divide in an uncontrolled manner. A new study from Uppsala University now shows how alterations in a cell's degradation hubs, called lysosomes, can cause abnormal cell growth. The results are published ...

Why cells need acidic lysosomes

Just like the body contains lungs, liver, and lymph nodes, so does each of the body's cells contain tiny specialized organs. Perhaps most peculiar among them are lysosomes—bubble-like sacks that act as part recycling bin, ...

Biological risk potential of nanoparticles studied

Carbon nanoparticles are a promising tool for biomedical applications, for example, for targeted transportation of biologically active compounds into cells. A team of researchers from the Physics, Medicine and Chemistry departments ...

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