Biomolecular condensates within cells found to have structure

Every cell contains millions of protein molecules. Some of them have the ability to phase-separate to form non-membrane-bound compartments, called biomolecular condensates, inside a cell. It has long been assumed that there ...

Artificial intelligence folds RNA molecules

For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial ...

Female urinary tract lactobaccilli can kill pathogenic bacteria

Lactobacilli that live in the human female urinary tract's microbiome are competitive and kill nearby pathogenic bacteria, according to the first study of its kind by a team led by microbiologist Dr. Tanya Sysoeva of The ...

Universal optothermal micro/nanoscale rotors

The fundamental rotation of micro and nano-objects is crucial for the functionality of micro and nanorobotics, as well as three-dimensional imaging and lab-on-a-chip systems. These optical rotation methods can function fuel-free ...

Determining the structure of small RNAs could inform future therapeutics

A new method allows researchers to determine the structure and abundance of "transfer RNAs" (tRNA)—small, highly structured and chemically modified RNAs involved in protein production—in living cells. Misfolding of tRNAs ...

Mass spectrometry-based draft of the mouse proteome

Proteins control and organize almost every aspect of life. The totality of all proteins in a living organism, a tissue or a cell is called the proteome. Using mass spectrometry, researchers at the Technical University of ...

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