Phase separation found in immune response within cells

Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new ...

Researchers develop new way to study neurodegenerative diseases

Some proteins in cells can separate into small droplets like oil droplets in water, but faults in this process may underlie neurodegenerative diseases in the brains of older people. Now, Rutgers researchers have developed ...

Research illuminates earliest part of phase separation

Scientists at St. Jude Children's Research Hospital are studying liquid-liquid phase separation (LLPS), a biophysical process through which proteins and nucleic acids in a cell are compartmentalized without a membrane. The ...

Improving data-independent acquisition proteomics

Proteomics produces enormous amounts of data, which can be very complex to analyze and interpret. The free software platform MaxQuant has proven to be invaluable for data analysis of shotgun proteomics over the past decade. ...

Dewdrops on a spiderweb reveal the physics behind cell structures

As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon ...

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