Embedding iron oxide into liposome bilayer to trigger ferroptosis

Ferroptosis, an iron-dependent regulated cell death process driven by excessive lipid peroxides and membrane injury, can enhance cancer vulnerability to chemotherapy. Lipid peroxidation of unsaturated lipids (UL) in biological ...

Simulations show fundamental interactions inside the cell

Actin filaments have several important functions inside cells. For one, they support the cell membrane by binding to it. However, scientists did not know exactly how the actin interacts with the membrane lipids. Simulations ...

Assembly of fluctuating molecules in artificial cell membrane

Lipids and membrane proteins existing in cell membranes, which are located at the outermost layer of cells, are responsible for recognizing extracellular environments and transferring that information inside the cell. Due ...

Little-known protein found to be key player

(PhysOrg.com) -- Italian and U.S. biologists this week report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining healthy cells. ...

Flipping lipids for cell transport-tubules

Researchers are getting closer to understanding the molecular processes that cause parts of cell membranes to morph into tiny tubes that can transport molecules in and out of cells.

Supercomputer simulation reveals new mechanism for membrane fusion

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.

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