80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health. However, evolutionary selection optimized natural chemicals to benefit their host, not for safety or efficacy in ...

Analyzing mol­e­c­u­lar struc­tures in more de­tail

Chemistry and structural biology use the standard methods of NMR spectroscopy (NMR = nuclear magnetic resonance) to examine the structure of molecules including large molecules like proteins in solution. The NMR active nuclei, ...

New macrolactone database could aid drug discovery, research

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones—large molecules used in drug development—which contains information ...

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