Molecule regulating sperm motility discovered

About 120 million unintended pregnancies occurred each year between 2015 and 2019 worldwide. While there are oral contraceptives for women, the development of oral contraceptives for men has not been successful. Now, a team ...

Novel switch protein that 'turns on' sperm for fertilization

For a sperm to fertilize an egg, the sperm must first mature in a man's epididymis. Now, an international team of researchers has identified a chain of events in which a protein secreted by the testis travels in the luminal ...

Changes to RNA aid the process of learning and memory

RNA carries pieces of instructions encoded in DNA to coordinate the production of proteins that will carry out the work to be done in a cell. But the process isn't always straightforward. Chemical modifications to DNA or ...

Faster, more efficient CRISPR editing in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the ...

Muscle gene may provide new treatments for obesity and diabetes

(PhysOrg.com) -- Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal ...

Worm genes KO'd

Knocking genes out of action allows researchers to learn what genes do by seeing what goes wrong without them. University of Utah biologists pioneered the field. Mario Capecchi won a Nobel Prize for developing knockout mice. ...

Knockouts in human cells point to pathogenic targets

(PhysOrg.com) -- Whitehead researchers have developed a new approach for genetics in human cells and used this technique to identify specific genes and proteins required for pathogens.

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