Feline genetics help pinpoint first-ever domestication of cats

Nearly 10,000 years ago, humans settling in the Fertile Crescent, the areas of the Middle East surrounding the Tigris and Euphrates rivers, made the first switch from hunter-gatherers to farmers. They developed close bonds ...

A key step toward growing human kidneys in the laboratory

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world. Being able to grow working kidney tissue in a laboratory could help accelerate medical treatments ...

Lead poisoning could reduce gene expression in humans

Scientists have unveiled a correlation between high blood lead levels in children and methylation of genes involved in haem synthesis and carcinogenesis, indicating a previously unknown mechanism for lead poisoning.

Researchers identify key steps in development of kidneys

The discovery of how certain key structures in the kidneys are formed could have important implications for treating renal fibrosis (or scarring), a feature of chronic kidney disease (CKD), according to a new study by a researcher ...

Sensors detect disease markers in breath

A small, thin square of an organic plastic that can detect disease markers in breath or toxins in a building's air could soon be the basis of portable, disposable sensor devices. By riddling the thin plastic films with pores, ...

How E. coli cells work in the human gut

(Phys.org) -- The bacterium Escherichia coli, commonly known as E. coli, has a duplicitous reputation. Scientists tell us that most strains of the microbe live peacefully in our guts or the guts of other mammals, munching ...

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Renal failure

Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems.

Biochemically, it is typically detected by an elevated serum creatinine. In the science of physiology, renal failure is described as a decrease in the glomerular filtration rate. When the kidneys malfunction, problems frequently encountered are abnormal fluid levels in the body, deranged acid levels, abnormal levels of potassium, calcium, phosphate, hematuria (blood in the urine) and (in the longer term) anemia. Long-term kidney problems have significant repercussions on other diseases, such as cardiovascular disease.

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