For millions of people with diabetes, insulin is essential medicine. But for some ocean-dwelling predators, insulin is a weapon. With a burst of venom, a fish-hunting cone snail can drop the blood sugar of its prey so precipitously ...
Biochemistry
Mar 15, 2022
0
359
A new study shows that the protein CHIP can regulate the insulin receptor more efficiently alone than in a paired state. In cellular stress situations, CHIP usually appears as a homodimer—an association of two identical ...
Cell & Microbiology
Sep 12, 2022
0
85
A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable ...
Biochemistry
Mar 25, 2022
0
24
A mother's response to stress can even influence her grandchildren.
Molecular & Computational biology
Oct 13, 2021
0
90
In a discovery that may further the understanding of diabetes and human longevity, scientists at Scripps Research have found a new biological mechanism of insulin signaling. Their study, involving the roundworm C. elegans, ...
Cell & Microbiology
Feb 25, 2020
0
203
Each year, rice in Asia faces a big threat from a sesame seed-sized insect called the brown planthopper. Now, a study reveals the molecular switch that enables some planthoppers to develop short wings and others long—a ...
Plants & Animals
Mar 18, 2015
0
28
Since its landmark discovery in 1922, insulin has improved the health and extended the lives of more than 500 million people worldwide with diabetes mellitus. Yet the question of how this key hormone binds to its target cells ...
Biochemistry
Aug 4, 2014
0
0
One enzyme regulates the body's insulin receptor, ensuring energy needed for function and survival. The other enables a bacterium to wreak havoc in the form of bubonic plague.
Biochemistry
Aug 22, 2013
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0
The androgen receptor in human cells inhibits fat accumulation, but its activity can be sabotaged by glucocorticoids, steroids that regulate fat deposition and are known drivers of obesity and insulin resistance, said researchers ...
Cell & Microbiology
Sep 20, 2012
0
0
(PhysOrg.com) -- A compound found in red wine, grapes and other fruits, and similar in structure to resveratrol, is able to block cellular processes that allow fat cells to develop, opening a door to a potential method to ...
Biochemistry
Apr 4, 2012
1
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