Unique mechanism protects pancreatic cells from inflammation in mice

Researchers from the University of Cologne have revealed a mechanism protecting pancreatic β-cells, which are crucial for insulin production from inflammatory cell death. The study investigated the role of receptor-interacting ...

Influenza virus-induced oxidized DNA activates inflammasomes

Both influenza virus M2, a proton-selective ion channel essential for efficient viral replication, and PB1-F2 protein, which localizes to the mitochondria and attenuates host antiviral immunity, are involved in the inflammatory ...

Re-trafficking proteins to fight Salmonella infections

When humans get infected by pathogenic bacteria, the body's immune system tries to eliminate the intruders. One way of doing this is by launching an inflammatory response—a cascade of events that includes the expression ...

A heart-healthy protein from bran of cereal crop

Foxtail millet is an annual grass grown widely as a cereal crop in parts of India, China and Southeast Asia. Milling the grain removes the hard outer layer, or bran, from the rest of the seed. Now, researchers have identified ...

From bugs to drugs

A new study led by Prof Shoumo Bhattacharya has decoded the structure of unique proteins found in tick saliva and created new ones not found in nature, paving the way for a new generation of "Swiss-army knife' anti-inflammatory ...

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