Unprecedented single-cell studies in virtual embryo

"How are the many different cell types in the body generated during embryonic development from an egg, which is only a single cell? This is one of the most fundamental questions in biology," explains Dr. Pierre Neveu, group ...

Cell membrane proteins imaged in 3-D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)—a U.S. Department of Energy (DOE) Office of Science User Facility at DOE's Brookhaven National Laboratory—have demonstrated ...

Study advances single-cell transcriptome profiling

With the goal of ensuring that single-cell RNA sequencing makes use of the best possible methods, an international group has benchmarked 13 methods. The group, led by Holger Heyn of the Centro Nacional de Análisis Genómico ...

Visualizing differences in RNA biology between single cells

A longstanding quest in medicine has been to understand how the same disease presents differently among various patients. Although it has been thought that a central aspect of these differences is a heterogeneity between ...

Bacteria form biofilms like settlers form cities

Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."

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