An LMU research team led by Nicolai Siegel has uncovered a mechanism that enables the parasite that causes sleeping sickness in humans to escape the attention of the immune system. The finding may also be relevant to other ...
Cell & Microbiology
Jan 12, 2021
0
17
A shapeshifting immune system protein called XCL1 evolved from a single-shape ancestor hundreds of millions of years ago. Now, researchers at the Medical College of Wisconsin (MCW) discovered the molecular basis for how this ...
Biochemistry
Jan 11, 2021
0
29
Using X-ray crystallography and cryo-electron microscopy, an international team of scientists unravel the atomic structure of the proteins P1 and P40/P90 which make up the "Nap" structure—a protein complex that the bacterium ...
Cell & Microbiology
Oct 14, 2020
0
12
Each year, the flu vaccine has to be redesigned to account for mutations that the virus accumulates, and even then, the vaccine is often not fully protective for everyone.
Cell & Microbiology
Oct 7, 2020
0
419
Despite decades of study, exactly how herpesviruses invade our cells remains something of a mystery. Now researchers studying one herpesvirus, the varicella zoster virus (VZV) that causes chicken pox, may have found an important ...
Biochemistry
Aug 19, 2020
0
92
A key set of proteins that help regulate hormones necessary for many essential functions in humans and other vertebrates have ancient origins in much simpler creatures such as sea cucumbers, says a new study published today ...
Molecular & Computational biology
Jun 9, 2020
0
283
The structure of enzymes determines how they control vital processes such as digestion or immune response. This is because the protein compounds are not rigid, but can change their shape through movable "hinges." The shape ...
Biochemistry
Apr 24, 2020
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33
Before CRISPR became a household name as a tool for gene editing, researchers had been studying this unique family of DNA sequences and its role in the bacterial immune response to viruses. The region of the bacterial genome ...
Molecular & Computational biology
Apr 20, 2020
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42
Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see how specific genetic mutations can combine ...
Biotechnology
Apr 14, 2020
1
991
Research led by the University of Southampton has revealed the fundamental features of the SARS-CoV-2 coronavirus that causes COVID19. The researchers have produced the first model of a spike of the virus which shows how ...
Cell & Microbiology
Apr 9, 2020
0
1303
