The colonization of the seafloor is one of the most important events in evolutionary history, leading to an explosive radiation and large-scale morphological diversification of marine phyla. Flatfishes are one of the most ...
Evolution
Apr 26, 2021
0
253
A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, ...
Plants & Animals
Mar 29, 2021
0
658
How do plants build resilience? An international research team led by the University of Göttingen studied the molecular mechanisms of the plant immune system. They were able to show a connection between a relatively unknown ...
Plants & Animals
Feb 16, 2021
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6
Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, ...
Biotechnology
Feb 11, 2021
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90
In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9—as a genetic dimmer switch for CRISPR-Cas9 ...
Cell & Microbiology
Jan 19, 2021
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33
Researchers from the University of Helsinki, Finland examined 48 Staffordshire Bull Terriers, of which eight dogs—four healthy and four atopic—were selected for RNA sequencing where their skin gene expression was compared ...
Veterinary medicine
Nov 13, 2020
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15
Gene therapy generally relies on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the case of CRISPR-based gene therapies, molecular scissors can then snip out a defective gene, add in a missing ...
Cell & Microbiology
Sep 3, 2020
0
27
At the start of her 2008 field season at El Parque El Piñalito in the Misiones province in northeastern Argentina, Ilaria Agostini knew something was terribly wrong. Agostini has studied Misiones' two howler monkey species ...
Plants & Animals
Aug 12, 2020
0
400
A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the worst prognosis among brain tumors, was successfully developed. In vivo experiments demonstrated that the combined use of epirubicin-encapsulating ...
Bio & Medicine
Aug 7, 2020
0
9
For frogs dying of the invasive chytridiomycosis disease, the leading cause of amphibian deaths worldwide, the genes responsible for protecting them may actually be leading to their demise, according to a new study published ...
Plants & Animals
Jul 23, 2020
0
6
