Cellular trash cans reveal the roles of proteins in disease

If we really want to know how our body's cells work—or don't work, in the case of disease—we might need to look beyond their genes and even beyond the proteins they are made of. We may need to start going through the ...

Novel tool developed to diagnose and monitor autoimmune disorders

Researchers from the Prokhorov General Physics Institute of the Russian Academy of Sciences and the Moscow Institute of Physics and Technology have developed a novel method for diagnosing and monitoring autoimmune disorders. ...

Nanovaccine boosts immunity in sufferers of metabolic syndrome

A new class of biomaterial developed by Cornell researchers for an infectious disease nanovaccine effectively boosted immunity in mice with metabolic disorders linked to gut bacteria – a population that shows resistance ...

Researchers parse the origins of hematopoietic stem cells

Researchers at the University of California, San Diego School of Medicine have identified a gene and a novel signaling pathway, both critical for making the first hematopoietic stem cells (HSCs) in developing vertebrate embryos. ...

Simulated gene therapy

In a recent issue of The Journal of Chemical Physics, published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the ...

New class of drugs for the reversible inhibition of proteasomes

As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they need the proteasome ...

Toxoplasma: the parasite that takes over our brains

A recurring fantasy in science fiction is the implantation of tiny elements in peoples' brains, which would be used to control and direct our actions and emotions. Regardless of the direction that technological development ...

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