Researchers use base editing to probe blood cell biology
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Cell & Microbiology
May 3, 2023
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11
A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach could also power the development of advanced ...
Cell & Microbiology
Apr 28, 2023
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156
A clever protein inside the immune system could be used as a "weapon" against a common bacteria that in extreme cases is responsible for causing deadly flesh-eating disease, scientists from the Australian National University ...
Cell & Microbiology
Apr 20, 2023
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A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the function of a unique enzyme, ANKLE1. ANKLE1 acts on chromatin bridges that are trapped ...
Cell & Microbiology
Apr 18, 2023
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370
"Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between ...
Cell & Microbiology
Apr 13, 2023
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50
Human skin is home to millions of microbes. One of these microbes, Staphylococcus aureus, is an opportunistic pathogen that can invade patches of skin affected by eczema, also known as atopic dermatitis.
Evolution
Apr 12, 2023
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47
Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract. While we have known for decades that ...
Cell & Microbiology
Apr 11, 2023
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43
In Brazil, a group of researchers supported by FAPESP created mutant forms of Salmonella to understand the mechanisms that favor colonization of the intestinal tract of chickens by these pathogenic bacteria and find better ...
Cell & Microbiology
Apr 11, 2023
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EPFL researchers have used a nanoplasmonics approach to observe the real-time production of cell secretions, including proteins and antibodies; an advancement that could aid in the development of cancer treatments, vaccines, ...
Bio & Medicine
Apr 11, 2023
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42
Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing ...
Bio & Medicine
Apr 3, 2023
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28