Study finds why many IVF embryos fail to develop

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...

A missing 'motor' causes human eggs to fail

Human eggs often contain the wrong number of chromosomes, leading to miscarriages and infertility. A research team led by Melina Schuh at the Max Planck Institute (MPI) for Multidisciplinary Sciences has discovered that human ...

When a chromosome is lost: How do human cells react to monosomy?

Human cells are usually diploid—they contain two sets of chromosome. Cells in which one chromosome is missing from the duplicated chromosome set are generally not viable. For a long time, the mechanisms responsible for ...

Evolutionary 'arms race' may help keep cell division honest

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, ...

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