In a study published in Nucleic Acids Research, the team of cancer researcher Francis Rodier, an Université de Montréal professor, shows for the first time that cellular senescence, which occurs when aging cells stop dividing, ...
Cell & Microbiology
Nov 9, 2021
0
218
BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the cellular system that repairs double-strand DNA breaks. Now, researchers from Japan have discovered a new way in which ...
Biotechnology
Jul 13, 2021
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11
Scientists from the lab of Franz Klein from the Department of Chromosome Biology at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, have now discovered that cells sometimes ...
Cell & Microbiology
Jun 9, 2021
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8
In a study with implications for chronic infections, Princeton researchers have described multiple pathways that some bacteria use to tolerate normally lethal antibiotic treatments. The findings overturn common assumptions ...
Cell & Microbiology
Apr 20, 2021
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89
Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the MRN complex—the cell's DNA scissors. Using purified yeast proteins, they demonstrated that phosphorylation ...
Biotechnology
Mar 10, 2021
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12
DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...
Molecular & Computational biology
Sep 24, 2020
0
31
Homologous recombination is an essential process of DNA repair to maintain genomic integrity of the organism. Now, researchers from Japan have identified mechanisms that choose between alternate pathways of DNA repair to ...
Evolution
Apr 30, 2020
0
17
One of the worst things that can happen to a cell is to end up with the wrong number of chromosomes. This can happen if something goes wrong during cell division, and it can lead to infertility, miscarriages, birth defects, ...
Cell & Microbiology
Oct 4, 2018
0
55
A new study provides more evidence that identical sections of DNA can match up with each other without the help of other molecules.
Biotechnology
Jul 20, 2016
0
45
(Phys.org)—A small team of researchers with the University of California has developed a way to use CRISPR/Cas9 to mimic mitotic recombination in yeast cells leading to a new way to map out genes and by doing so, determine ...
