Within every cell in our body, our DNA is tightly bundled with proteins to form structures known as chromosomes. The commonly known shape of a chromosome relates to an X-shaped appearance in many organisms. The formation ...
Plants & Animals
Feb 14, 2024
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9
In a new study published in the Proceedings of the National Academy of Sciences, University of Utah (the U) biologists have developed a method for illuminating the intricate interactions of the synaptonemal complex in the ...
Cell & Microbiology
Jan 3, 2024
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41
The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 method can also result in unintended ...
Biotechnology
Sep 15, 2023
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58
Meiotic recombination assures genetic variation during breeding. During meiotic prophase I, chromosomes are organized in a loop-base array by a proteinaceous structure called meiotic chromosome axis, which is critical for ...
Plants & Animals
Mar 13, 2023
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7
Collaborating research groups in China have developed a novel technique, called DNA End tailing and sequencing (DEtail-seq), for meiotic DNA double-strand break (DSB) profiling.
Cell & Microbiology
Mar 2, 2023
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4
In most higher organisms, including humans, every cell carries two versions of each gene, which are referred to as alleles. Each parent passes on one allele to each offspring. As they are linked together on chromosomes, adjacent ...
Cell & Microbiology
Oct 24, 2022
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136
Unisexual reproduction lacks meiotic recombination, resulting in the accumulation of deleterious mutations and hindering the creation of genetic diversity. Thus, unisexual taxa are commonly considered an evolutionary dead ...
Evolution
Jul 11, 2022
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26
Testicles of most mammals are cooled in the scrota, and elevated testicular temperatures lead to spermatogenesis failure and male infertility. A research team led by Shosei Yoshida at the National Institute for Basic Biology ...
Cell & Microbiology
May 26, 2022
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26
Synaptonemal complex (SC) assembly between paired homologous chromosomes plays a vital role in ensuring correct homologous recombination during meiosis. However, the mechanisms underlying the genetic regulation of SC assembly ...
Plants & Animals
Nov 10, 2021
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33
Scientists from the lab of Franz Klein from the Department of Chromosome Biology at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, have now discovered that cells sometimes ...
Cell & Microbiology
Jun 9, 2021
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