New CRISPR tech targets human genome's complex code
Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle.
Biotechnology
Feb 9, 2021
0
146
Page 6 - News tagged with histones
Researchers reveal the first cryo-EM structures of NSD2 and NSD3 in complex with nucleosome
The nuclear receptor–binding SET Domain (NSD) family protein is closely connected with many cancers. However, their molecular mechanism remains unknown.
Biotechnology
Dec 24, 2020
0
193
How epigenetic switches control gene expression
Scientists at Tokyo Institute of Technology have deciphered how to quantitatively assess the effects of specific epigenetic changes on the rate of transcription by developing a mathematical model. Using their method, they ...
Biotechnology
Dec 11, 2020
0
83
New activity found for CHD7, a protein factor vital in embryonic development
Research by Kai Jiao, M.D., Ph.D., and colleagues at the University of Alabama at Birmingham and in Germany has yielded fundamental insights into the causes of severe birth defects known as CHARGE syndrome cases. These congenital ...
Molecular & Computational biology
Dec 3, 2020
0
17
Chemical memory in plants affects chances of offspring survival
Researchers at the University of Warwick have uncovered the mechanism that allows plants to pass on their 'memories' to offspring, which results in growth and developmental defects.
Plants & Animals
Dec 1, 2020
0
35
Histone degradation after DNA damage enhances repair
DNA damage can occur anywhere in the genome, but most DNA is wrapped around nucleosomes making it inaccessible to the repair machinery. Researchers from the Gasser group now show that DNA damage induces histone depletion, ...
Molecular & Computational biology
Sep 24, 2020
0
31
Histone H3-H4 tetramer found to be a copper reductase enzyme
A team of researchers at the University of California has found that the histone H3-H4 tetramer is a copper reductase enzyme. In their paper published in the journal Science, the group describes two experiments they carried ...
Team decodes another piece of the histone code puzzle
Inside our cells, DNA is tightly packed and spooled around proteins called histones. Packaging DNA in this way allows large amounts of genetic material to exist inside the cell in a final form called chromatin. Tiny enzymes ...
Cell & Microbiology
Jun 9, 2020
0
25
Mothers ensure their offspring's success through epigenetics
Parents pass genes along to their offspring traits that equip them for life. In recent years, research has shown that the reality is much more complex and that parents endow much more than just genes. A new study in Cell ...
Evolution
Jun 4, 2020
0
1055
How plants forget: New work uncovers how epigenetic marks are specifically reset in sperm
Although they do it differently than humans, plants also have memories. For example, many plants can sense and remember prolonged cold in the Winter to ensure they flower at the right time during the Spring. This so-called ...
Plants & Animals
May 14, 2020
0
80
