The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical ...
Cell & Microbiology
Sep 28, 2009
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(PhysOrg.com) -- In the Japanese art of paper folding, a series of folds can make the same sheet of paper into a ballerina or baby elephant. But try unfolding the baby elephant and making it into a ballerina. It’s like ...
Cell & Microbiology
May 14, 2009
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The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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Aging is known to involve epigenetic histone modifications, which are associated with transcriptional changes, occurring throughout the entire lifespan of an individual.
Molecular & Computational biology
Jun 30, 2022
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A joint research team led by Professor Ja Yil Lee (School of Life Sciences, UNIST) and Professor Ji-Joon Song (Department of Biological Sciences, KAIST) has unveiled the structure and mechanism of proteins that are highly ...
Biotechnology
Mar 10, 2020
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A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman ...
Molecular & Computational biology
Dec 5, 2019
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4
Researchers at the Institute for Research in Biomedicine (IRB Barcelona), Cambridge University and New York University, led by Modesto Orozco, Group Leader at IRB Barcelona, Director of Life Sciences at the Barcelona Supercomputing ...
Biochemistry
Jul 28, 2015
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24
Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
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