The DNA in the 23 pairs of chromosomes in each of the billions of cells of the human body is so tightly packed that it would measure six feet in length if stretched end to end. A genome of this size can squeeze into a cell's ...
Cell & Microbiology
Apr 9, 2009
1
0
LMU molecular biologist Gunnar Schotta has investigated which mechanisms prevent endogenous retroviruses from becoming overly active.
Molecular & Computational biology
Sep 19, 2022
0
4
A study lead by SciLifeLab Fellow Simon Elsässer elucidates the mechanism of a peculiar type of heterochromatin, used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic ...
Cell & Microbiology
Oct 9, 2020
0
8
How can human cells pack 3-meter-long DNA into their tiny nuclei and unpack it only where and when it is needed? This fascinating process is far from being completely understood.
Biotechnology
Feb 5, 2020
0
8
The genetic material of our cells—DNA—exists in a high-order structure called chromatin. Chromatin consists of DNA wrapped around histone proteins and efficiently packs DNA into a small volume. Moreover, using a spool ...
Molecular & Computational biology
Jan 23, 2020
0
19
Researchers have used mass spectroscopy to determine the absolute copy numbers of nuclear proteins and histone modifications in the Drosophila embryo. The results provide new insights into the mechanisms of animal development.
Plants & Animals
Oct 22, 2019
0
4
By using proteins that naturally bind and arrange DNA inside cells, a KAUST-led team has devised a plug-and-play strategy for building stable, custom-designed nanostructures.
Nanomaterials
Oct 14, 2019
0
29
Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.
Biochemistry
May 17, 2018
0
6
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
0
9
A group of researchers from the Institute of Bioorganic Chemistry of the RAS and Moscow State University, in collaboration with the University of Utah, has for the first time successfully made use of the FRET microscopy method ...
Cell & Microbiology
Dec 6, 2016
0
5
