(Phys.org) —Last month, researchers reported the creation of the first primitive brain-like structures made from human stem cells. To create the complex morphology of these cerebral organoids, cells within a proliferating ...
The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, and hints ...
Cell & Microbiology
Sep 16, 2013
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(Phys.org) —The ability of a cell to move, replicate, and recast itself according to the needs of the organism which it serves, comes at it price. The extreme flexibility of cells takes its origin from the constant turnover ...
Researchers at the IMP Vienna discovered that cohesin stabilizes DNA. Jan-Michael Peters and his team at the Research Institute of Molecular Pathology (IMP) found that the structure of Chromosomes is supported by a kind of ...
Cell & Microbiology
Aug 26, 2013
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The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism that allows chromosomal ...
Biochemistry
May 23, 2013
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Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils. When these spool-like proteins aren't made correctly, ...
Cell & Microbiology
Mar 24, 2013
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Every gene in the nucleus of an animal or plant cell is packaged into a beads-on-a-string like structure called nucleosomes: the DNA of the gene forms the string and a complex of proteins called histones forms the beads around ...
Biotechnology
Feb 11, 2013
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Histone proteins are the proteins that package DNA into chromosomes. Every time the cell replicates its DNA it must make large amounts of newly made histones to organize DNA within the nucleus.
Cell & Microbiology
Jan 17, 2013
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Researchers from the UK and Australia have uncovered a new element of the honeybee's genetic makeup, which may help to explain why bees are so sensitive to environmental changes.
Plants & Animals
Dec 11, 2012
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(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated the histone modifications that lead to the sequestration of silent genes at the nuclear periphery. In a study published ...
Cell & Microbiology
Aug 31, 2012
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