Related topics: heart disease · heart

Understanding congenital heart defects, one chicken at a time

Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...

Study reveals soil influence on well water manganese levels

Utilizing a wide range of analytic tools, researchers at North Carolina State University have figured out why pockets of the southeastern Piedmont region contain high concentrations of manganese in well water, particularly ...

True love: How transcription factors interact to create a heart

Scientists at the Gladstone Institutes have discovered that three transcription factors—proteins that direct gene expression—interact with each other and the genome to influence how a heart forms in an embryo. Without ...

New mouse model reveals a mystery of Duchenne muscular dystrophy

Children with Duchenne muscular dystrophy often die as young adults from heart and breathing complications. However, scientists have been puzzled for decades by the fact that laboratory mice bearing the same genetic mutation ...

New insight into the regulation of stem cells and cancer cells

Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important ...

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Congenital heart defect

A congenital heart defect (CHD) is a defect in the structure of the heart and great vessels of a newborn. Most heart defects either obstruct blood flow in the heart or vessels near it or cause blood to flow through the heart in an abnormal pattern, although other defects affecting heart rhythm (such as long QT syndrome) can also occur. Heart defects are among the most common birth defects and are the leading cause of birth defect-related deaths.

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