WEHI researchers have revealed how an "accordion effect" is critical to switching off genes, in a study that transforms the fundamentals of what we know about gene silencing.
Molecular & Computational biology
Apr 5, 2022
0
89
Researchers at the RIKEN Brain Science Institute in Japan engineered a fluorescent protein that rapidly assembles into large crystals inside living cells, and showed that cells actively targeted the crystals for degradation. ...
Cell & Microbiology
Mar 12, 2015
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8
Researchers at the University of Gothenburg, Sweden, have developed a new method to study single cells while exposing them to controlled environmental changes. The unique method, where a set of laser tweezers move the cell ...
General Physics
May 15, 2009
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0
Translation, a process that expresses the genetic information from messenger RNA (mRNA) to protein, is vital to maintain cellular protein homeostasis. To synthesize functional proteins and avoid toxic translation products, ...
Molecular & Computational biology
Dec 20, 2022
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168
A group of researchers led by Tomoji Mashimo, Associate Professor, Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University and Kazuto Yoshitomi, Assistant Professor, Mouse Genomics Resource ...
Biotechnology
Mar 24, 2016
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2
Traditionally, the study of diseases at the molecular level has required scientists to extract cells and tissues from animal models and then look for clues in the samples that can determine the mechanisms underlying the disease ...
Optics & Photonics
Sep 21, 2016
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9
Scientists from the Skolkovo Institute of Science and Technology (Skoltech), the Institute of Bioorganic Chemistry (IBCh RAS) and Lomonosov Moscow State University (MSU) undertook a detailed study on green-to-red photoconversion ...
Molecular & Computational biology
Sep 11, 2020
0
3
The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which ...
Cell & Microbiology
Jun 25, 2024
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18
Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease. The absorption of intestinal ...
Molecular & Computational biology
Mar 28, 2023
0
3
Ding! The courier hands me an unassuming brown box with "live animals" plastered on the side. I begin carefully unboxing. The cardboard exterior gives way to a white polystyrene clamshell, cloistering a pearly sphere-shaped, ...
Plants & Animals
Oct 2, 2023
0
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