Evading cell death

Cancer cells can develop resistance to the treatments designed to eliminate them. Several studies have linked stress granules (SGs), cell organelles that form transiently in response to extracellular stress, to this phenomenon. ...

Accelerated reactions in condensed bio-matter?

HITS researcher Dr. Kashif Sadiq explores ribonucleoprotein granules, a condensed form of bio-matter found inside cells. He investigates whether the rate of enzymatic reactions in these membrane-less granules is accelerated. ...

Study expands possibilities for treating neurological diseases

Researchers in Japan have gained valuable insights into 'stress granules'—clumps of RNAs and proteins that form when cells are stressed by factors such as heat, toxins and viruses, deepening the understanding of proteins ...

The big clean up after stress

Toxic substances, nutrient shortage, viral infection, heat and many other events trigger stress responses in cells. In such cases, the affected cells launch a programme which tries to protect them against stress-related damages. ...

Jumping genes have essential biological functions

"Alu" sequences are small repetitive elements representing about 10% of our genome. Because of their ability to move around the genome, these "jumping genes" are considered as real motors of evolution. However, they were ...

Growing functioning brain tissue in 3D

Researchers at the RIKEN Center for Developmental Biology in Japan have succeeded in inducing human embryonic stem cells to self-organize into a three-dimensional structure similar to the cerebellum, providing tantalizing ...

A protein provides stress relief for cells

German researchers have shown a new mechanism via which cells defend themselves against stress. Dr. Kathrin Thedieck and Birgit Holzwarth from the Institute of Biology III and the Cluster of Excellence BIOSS Centre for Biological ...

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