Breakthrough could lead to drugs that better combat 'superbugs'

(Phys.org)—In the never-ending battle between antibiotic developers and the bacteria they fight, scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory have made a key breakthrough that could allow ...

Mapping the 3-D geometry of SARS-CoV-2's genome

The novel coronavirus uses structures within its RNA to infect cells. Scientists have now identified these configurations, generating the most comprehensive atlas to date of SARS-CoV-2's genome.

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

New mechanism for genome unpacking in stem cells

Scientists at Karolinska Institutet and Gurdon Institute in Cambridge, United Kingdom have identified a novel mechanism that allows pluripotent stem cells to maintain their genome in an unpacked state, and thereby maintain ...

Study reveals DNA 'grammar'

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order. This was the finding of a study recently published in Genome Biology by Luca Nanni, Ph.D. student ...

Building a complete metabolic model

Investigators at Burnham Institute for Medical Research, University of California, San Diego, The Scripps Research Institute, Genomics Institute of the Novartis Research Foundation and other institutions have constructed ...

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