Simulated gene therapy

In a recent issue of The Journal of Chemical Physics, published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the ...

Circular RNAs more common than previously thought

In the classical model of gene expression, the genetic script encoded in our genomes is expressed in each cell in the form of RNA molecules, each consisting of a linear string of chemical "bases". It may be time to revise ...

Enzymes allow DNA to swap information with exotic molecules

(Phys.org) —The discovery of the Rosetta Stone resolved a longstanding puzzle, permitting the translation of Egyptian hieroglyphs into Ancient Greek. John Chaput, a researcher at Arizona State University's Biodesign Institute ...

The birth of a bacterial tRNA gene

Translation is the process by which genetic information is converted into proteins, the workhorses of the cell. Small molecules called transfer RNAs (tRNAs) play a crucial role in translation; they are the adapter molecules ...

Laser spotlight reveals machine 'climbing' DNA

(Phys.org)—New imaging technology has revealed how the molecular machines that remodel genetic material inside cells 'grab onto' DNA like a rock climber looking for a handhold.

Cellular metabolism self-adapts to protect against free radicals

Oxygen-consuming organisms obtain energy through cellular respiration, which is the transformation of carbohydrates and oxygen into carbon dioxide and water. This process also produces toxic oxygen radicals which must be ...

New calculations solve an old problem with DNA

The normal (B-form) DNA will switch to left-handed DNA when it is physically twisted, or when a lot of salt is added to the solution. Researchers at the University of Luxembourg were able to accurately calculate for the ...

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